The main issue as I see it is that Reed's inventions normally arise out of trying to do something else. Who else is a mutate (all mutants are mutates, not all mutates are mutants) who has powers he doesn't really want and who Reed has been trying to help for years?
That'd be The Thing.
Reed probably came up with it while trying to solve for that problem. By removing his ability to even recall how to create it, they've probably also removed his ability to help his friend. And given that Xavier basically committed psychic rape, Reed will probably has no qualms about ripping everything he needs out of Cerebro until he gets what he's looking for. And since Ororo's only defining characteristic since her marriage to T'Challa has been her supreme arrogance, the ongoing question is going to be how long Doom allows Cerebro's backups to exist at all.
Ororo has always been a hothead, but you'd think Charles would have more sense than that.
There are two rules when dealing with FF adjacent people:
Rule 1. Doesn't matter who starts it, Reed finishes it.
Rule 2. If you eff with Doom and he doesn't immediately retaliate, it's because he is going to make you suffer and wants it to hurt as much as possible.