Actually, a follow-up here. I remembered thinking that some of Defenders could take place during the Mayor Murdock storyline and I just remembered why. Diamondback appears in Daredevil 598, which suggests that Defenders 7 onward takes place after. I think the best solution (I'll edit this post if I'm wrong) would be to put the end of the series during the brief time Matt was mayor. Let me know what everyone thinks.
ETA: In Daredevil 600, Iron Fist refers to Matt Murdock and Daredevil as separate people. So he the reveal hadn't happened yet or he knew but didn't want to let others know and played along. I'm thinking the best way to do it would be Defenders 1-6, Secret Empire, Supreme, Land of the Blind, Defenders 7-8, Mayor Fisk (with allowances for overlap between Defenders 7 and Daredevil 595), Mayor Murdock, Defenders 9-10, Infinity Countdown: Daredevil, Hunt for Wolverine, War of the Realms, Death of Daredevil.