I'm expecting the upcoming run to suffer from MCU synergy. We already had Okoye come back with the same look and title as MCU Okoye, Shuri losing the white hair for a look similar to MCU Shuri and sometimes given her personality, versions of Nakia and M'Baku being introduced as allies with Nakia being used as a love interest. Whoever is taking over in the sequel will definitely be getting a big push on the comics side by shoehorning them in different comics and by giving them their own book. I don't think that T'Challa will be temporarily replaced in his own book maybe overshadowed by whomever the MCU is pushing but it wouldn't surprise me if Marvel chooses to sideline him for synergy for a while .
Who knows maybe Marvel will let Ridley write a good series about T'Challa with little synergy.