The Avengers comic have been teasing for some time a war between the forces of the multiversal Masters of Evil and the Avenger Prime, a mysterious protector of all realities who sends Deathlocks as his agents to protect worlds against threats. So far, we have only seen him from afar.
So who do you think this Avenger Prime, the most important Avenger in the multiverse, can possibly be? I place my bets on the Iron Man of Earth-199999. Yes, I know he's dead, but as the Infinity Stones are involved, there are many ways that can be retconned somehow.